{"product_id":"tirzepatide","title":"TIRZEPATIDE","description":"\u003cp data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003e\u003cspan class=\"citation-26\"\u003eTirzepatide\u003c\/span\u003e\u003c\/b\u003e\u003cspan class=\"citation-26 citation-end-26\"\u003e\u003cspan\u003e \u003c\/span\u003eis a synthetic, linear 39-amino acid peptide that functions as a dual agonist for the Glucose-Dependent Insulinotropic Polypeptide (GIP) and Glucagon-Like Peptide-1 (GLP-1) receptors.\u003csup class=\"superscript\" data-turn-source-index=\"6\"\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan class=\"citation-25 citation-end-25\"\u003eStructurally, it is based on the native GIP sequence but modified to bind both incretin receptors with high affinity.\u003csup class=\"superscript\" data-turn-source-index=\"7\"\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan class=\"citation-24 citation-end-24\"\u003eA C20 fatty diacid moiety is attached via a hydrophilic linker, which facilitates albumin binding and extends the compound's half-life in biological systems.\u003csup class=\"superscript\" data-turn-source-index=\"8\"\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"15\"\u003e\u003cspan class=\"citation-23 citation-end-23\"\u003eThe primary mechanism of action involves the simultaneous activation of GIP and GLP-1 signaling pathways.\u003csup class=\"superscript\" data-turn-source-index=\"9\"\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan class=\"citation-22 citation-end-22\"\u003eResearch indicates that this dual agonism may synergistically influence glucose homeostasis by enhancing glucose-dependent insulin secretion and suppressing glucagon release.\u003csup class=\"superscript\" data-turn-source-index=\"10\"\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan class=\"citation-21 citation-end-21\"\u003e\u003cspan\u003eFurthermore, interactions with receptors in the central nervous system (CNS) have been observed to modulate gastric emptying rates and signaling pathways associated with satiety and metabolic regulation.\u003c\/span\u003e\u003csup class=\"superscript\" data-turn-source-index=\"11\"\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Liberty Labs USA","offers":[{"title":"5 MG","offer_id":47909780324600,"sku":"TIRZ-LYO-00X-1","price":46.1,"currency_code":"USD","in_stock":false},{"title":"10 MG","offer_id":47909780357368,"sku":"TIRZ-LYO-00X-2","price":82.0,"currency_code":"USD","in_stock":false},{"title":"15 MG","offer_id":47909780390136,"sku":"TIRZ-LYO-00X-3","price":117.8,"currency_code":"USD","in_stock":false},{"title":"20 MG","offer_id":47909780422904,"sku":"TIRZ-LYO-00X-4","price":148.6,"currency_code":"USD","in_stock":false},{"title":"30 MG","offer_id":47909780455672,"sku":"TIRZ-LYO-00X-5","price":210.0,"currency_code":"USD","in_stock":false},{"title":"60 MG","offer_id":47909780488440,"sku":"TIRZ-LYO-00X-6","price":389.3,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/0773\/3240\/files\/TIRZEPATIDE5MG.jpg?v=1768812022","url":"https:\/\/www.libertylabusa.com\/products\/tirzepatide","provider":"Liberty Labs USA","version":"1.0","type":"link"}