{"product_id":"sermorelin","title":"SERMORELIN","description":"\u003cp data-path-to-node=\"15\"\u003e\u003cspan class=\"citation-7 citation-end-7\"\u003e[SERMORELIN] is a synthetic peptide analogue corresponding to the amino-terminal segment (residues 1–29) of the naturally occurring human Growth Hormone-Releasing Hormone (GHRH).\u003csup class=\"superscript\" data-turn-source-index=\"4\"\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan class=\"citation-6 citation-end-6\"\u003eThis specific sequence, often denoted as GRF 1-29, represents the shortest fully functional fragment of GHRH capable of binding to the Growth Hormone-Releasing Hormone Receptor (GHRHr) in the anterior pituitary.\u003csup class=\"superscript\" data-turn-source-index=\"5\"\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"16\"\u003eUpon introduction to the pituitary somatotrophs, [SERMORELIN] activates the adenylate cyclase signaling pathway.\u003cspan\u003e \u003c\/span\u003e\u003cspan class=\"citation-5 citation-end-5\"\u003eThis interaction increases intracellular cyclic adenosine monophosphate (cAMP), which subsequently stimulates the transcription and pulsatile secretion of endogenous growth hormone (GH).\u003csup class=\"superscript\" data-turn-source-index=\"6\"\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan class=\"citation-4 citation-end-4\"\u003e\u003cspan\u003eUnlike exogenous recombinant Human Growth Hormone (rHGH), which suppresses the body's natural production via a negative feedback loop, [SERMORELIN] maintains the integrity of the hypothalamic-pituitary-somatotropic axis, allowing for regulation by somatostatin to prevent supraphysiological overdose in research models.\u003c\/span\u003e\u003csup class=\"superscript\" data-turn-source-index=\"7\"\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Liberty Labs USA","offers":[{"title":"5 MG","offer_id":47909791858936,"sku":"PEP-SRM-2MG-1","price":49.2,"currency_code":"USD","in_stock":false},{"title":"10 MG","offer_id":47909791891704,"sku":"PEP-SRM-2MG-2","price":98.4,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/0773\/3240\/files\/SERMORELIN5MG.jpg?v=1768813476","url":"https:\/\/www.libertylabusa.com\/products\/sermorelin","provider":"Liberty Labs USA","version":"1.0","type":"link"}