{"product_id":"selank","title":"SELANK","description":"\u003cp data-path-to-node=\"15\"\u003e[SELANK] is a synthetic heptapeptide derivative of the endogenous peptide\u003cspan\u003e \u003c\/span\u003e\u003cb data-path-to-node=\"15\" data-index-in-node=\"74\"\u003eTuftsin\u003c\/b\u003e\u003cspan\u003e \u003c\/span\u003e(a fragment of the IgG heavy chain). It was synthesized by elongating the Tuftsin sequence (Thr-Lys-Pro-Arg) with a C-terminus tripeptide (Pro-Gly-Pro) to improve metabolic stability and extend half-life.\u003c\/p\u003e\n\u003cp data-path-to-node=\"16\"\u003eThe primary mechanism of action identified in research settings involves the\u003cspan\u003e \u003c\/span\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"77\"\u003eallosteric modulation of the GABAergic system\u003c\/b\u003e. Unlike classical benzodiazepines, [SELANK] does not bind directly to the orthosteric GABA-A receptor site but appears to modulate the receptor's conformational state, enhancing the affinity for endogenous GABA. Additionally, studies suggest the peptide influences monoaminergic neurotransmission, specifically regulating the metabolism of serotonin (5-HT) and dopamine in the cerebral cortex. It is also noted for its ability to increase the expression of Brain-Derived Neurotrophic Factor (BDNF) in the hippocampus.\u003c\/p\u003e","brand":"Liberty Labs USA","offers":[{"title":"5 MG","offer_id":47934681710840,"sku":"PEP-SEL-10MG-1","price":25.6,"currency_code":"USD","in_stock":false},{"title":"10 MG","offer_id":47934681743608,"sku":"PEP-SEL-10MG-2","price":46.1,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/0773\/3240\/files\/SELANK5MG.jpg?v=1768817492","url":"https:\/\/www.libertylabusa.com\/products\/selank","provider":"Liberty Labs USA","version":"1.0","type":"link"}