{"product_id":"hmg","title":"HMG","description":"\u003cp data-path-to-node=\"18\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"18\"\u003e\u003cspan class=\"citation-3\"\u003eHMG (Human Menopausal Gonadotropin)\u003c\/span\u003e\u003c\/b\u003e\u003cspan class=\"citation-3 citation-end-3\"\u003e\u003cspan\u003e \u003c\/span\u003eis a purified preparation of gonadotropins extracted from the urine of postmenopausal females, consisting primarily of Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH).\u003csup data-turn-source-index=\"7\" class=\"superscript\"\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003eIn research settings, it is utilized as a potent agonist of the gonadotropin receptors located in the gonads (ovaries and testes)\u003c\/p\u003e\n\u003cp data-path-to-node=\"19\"\u003eThe primary mechanism of action involves the binding of FSH and LH subunits to G-protein coupled receptors (GPCRs) on granulosa cells in ovarian follicles or Sertoli and Leydig cells in the testes. Upon binding, the peptide complex activates the adenylate cyclase signaling pathway, increasing intracellular cAMP levels. This cascade promotes gametogenesis and steroidogenesis.\u003cspan\u003e \u003c\/span\u003e\u003cspan class=\"citation-2 citation-end-2\"\u003e\u003cspan\u003eUnlike recombinant FSH alone, HMG provides dual-receptor stimulation, which studies suggest may be critical for full follicular maturation and steroid biosynthetic support in certain biological models.\u003c\/span\u003e\u003csup data-turn-source-index=\"8\" class=\"superscript\"\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Liberty Labs USA","offers":[{"title":"Default Title","offer_id":47890944655608,"sku":"HMG-075-IU","price":46.1,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/0773\/3240\/files\/HMG75IU.jpg?v=1768808774","url":"https:\/\/www.libertylabusa.com\/products\/hmg","provider":"Liberty Labs USA","version":"1.0","type":"link"}