{"product_id":"ghk-cu","title":"GHK-CU","description":"\u003cp data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003e\u003cspan class=\"citation-14\"\u003e[GHK-Cu]\u003c\/span\u003e\u003c\/b\u003e\u003cspan class=\"citation-14 citation-end-14\"\u003e\u003cspan\u003e \u003c\/span\u003eis a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine.\u003csup class=\"superscript\" data-turn-source-index=\"7\"\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan class=\"citation-13 citation-end-13\"\u003eOriginally isolated from human plasma in 1973, it has been identified as a modulator of the extracellular matrix (ECM).\u003csup class=\"superscript\" data-turn-source-index=\"8\"\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan class=\"citation-12 citation-end-12\"\u003eThe peptide possesses a high affinity for copper (II) ions, forming a chelate that allows it to function as a carrier mechanism, delivering copper into cells where it acts as a co-factor for various enzymatic processes.\u003csup class=\"superscript\" data-turn-source-index=\"9\"\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"15\"\u003e\u003cspan class=\"citation-11 citation-end-11\"\u003eIn vitro analysis suggests the primary mechanism of action involves the regulation of metalloproteinases (MMPs) and their tissue inhibitors (TIMPs).\u003csup class=\"superscript\" data-turn-source-index=\"10\"\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan class=\"citation-10 citation-end-10\"\u003eBy modulating this balance, [GHK-Cu] is theorized to influence the breakdown and synthesis of collagen, elastin, and glycosaminoglycans.\u003csup class=\"superscript\" data-turn-source-index=\"11\"\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003eFurthermore, the peptide has been observed to interact with gene expression pathways; specific studies using the Broad Institute Connectivity Map indicate that [GHK-Cu] may induce a ≥50% change in the expression of over 4,000 human genes, generally shifting them toward a state of repair and regeneration.\u003c\/p\u003e","brand":"Liberty Labs USA","offers":[{"title":"50 MG","offer_id":47909782946040,"sku":"PEP-GHKCU-050","price":38.9,"currency_code":"USD","in_stock":true},{"title":"100 MG","offer_id":47909782978808,"sku":"PEP-GHKCU-051","price":63.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/0773\/3240\/files\/GHK-CU50MG_9fb2064a-3638-4a09-b8c5-26a889e91151.jpg?v=1769015953","url":"https:\/\/www.libertylabusa.com\/products\/ghk-cu","provider":"Liberty Labs USA","version":"1.0","type":"link"}